Credelio® Family of Brands

Monthly Protection in a Chewable Tablet
Whether you need all-in-one parasite protection for your dog or flea and
tick protection for your dog or cat, the Credelio® family of
products has you covered. Best of all, each formula comes in a monthly
chewable tablet.
Ask your veterinarian which is the right Credelio product for your dog or cat.
Exclusive Member Savings on Credelio
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Credelio Quattro™ for Dogs
Protects against ticks, fleas, heartworm disease, tapeworms, roundworms and hookworms (Uncinaria stenocephala) in dogs and puppies at least 8 weeks of age and weighing 3.3 lbs. or more.
Credelio for Dogs
Treats and prevents flea infestations and treats and controls tick infestations in dogs and puppies at least 8 weeks of age and weighing 4.4 lbs. or more.


Credelio for Cats
Treats and prevents flea infestations and treats and controls tick infestations in cats and kittens at least 8 weeks of age and weighing 2.0 lbs. or more.

Credelio Quattro Covers 6 Types of Parasites1, Unlike Other Chewable Brands That Only Cover 5
Credelio Quattro is the first and only prescription tablet that protects against ticks, fleas, heartworm disease, and three intestinal worms that can be passed to humans — tapeworms, roundworms, and hookworms (Uncinaria stenocephala).

Indications
Credelio Quattro is indicated for the prevention of heartworm disease and the
treatment and control of roundworm, hookworm (Uncinaria stenocephala)
and tapeworm infections. Credelio Quattro kills adult fleas and is indicated for
the treatment and prevention of flea infestations and the treatment and control
of tick infestations for 1 month in dogs and puppies 8 weeks of age and older
and weighing 3.3 pounds or greater.
Important Safety Information
Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class
and has been associated with neurologic adverse reactions like tremors, ataxia,
and seizures even in dogs without a history of seizures. Use with caution in
dogs with a history of seizures or neurologic disorders. Dogs should be tested
for existing heartworm infections before Credelio Quattro administration as it
is not effective against adult D. immitis. The safe use in breeding,
pregnant, or lactating dogs has not been evaluated. The most frequently reported
adverse reactions in clinical trials were vomiting and diarrhea. For complete
safety information, please see Credelio Quattro product label or ask your
veterinarian.
CREDELIO FOR DOGS
Indications
Credelio kills adult fleas and is indicated for the treatment and prevention of
flea infestations and treatment and control of tick infestations
(lone star tick, American dog tick, black-legged tick, and brown dog tick) for
one month in dogs and puppies 8 weeks and older and 4.4 pounds or greater.
Important Safety Information
Lotilaner is a member of the isoxazoline class of drugs. This class has been
associated with neurologic adverse reactions including tremors, incoordination,
and seizures. Seizures have been reported in dogs receiving this class of drugs,
even in dogs without a history of seizures. Use with caution in dogs with a
history of seizures or neurologic disorders. The safe use of Credelio in
breeding, pregnant or lactating dogs has not been evaluated. The most frequently
reported adverse reactions are weight loss, elevated blood urea nitrogen,
increased urination, and diarrhea. For complete safety information, please see
Credelio product label or ask your veterinarian.
CREDELIO FOR CATS
Indications
Credelio CAT kills adult fleas and is indicated for the treatment and prevention
of flea infestations for one month in cats and kittens 8 weeks of age and older
and weighing 2 pounds or greater. Credelio CAT is also indicated for treatment
and control of black-legged tick infestations for one month in cats and kittens
6 months of age and older and weighing 2 pounds or greater.
Important Safety Information
Lotilaner is a member of the isoxazoline class of drugs. This class has been
associated with neurologic adverse reactions including tremors, incoordination,
and seizures. Neurologic adverse reactions have been reported in cats receiving
isoxazoline class drugs, even in cats without a history of neurologic disorders.
Use with caution in cats with a history of neurologic disorders. The safety of
Credelio CAT has not been established in breeding, pregnant and lactating cats.
The effectiveness of Credelio CAT against black-legged ticks in kittens less
than 6 months of age has not been evaluated. The most frequently reported
adverse reactions are weight loss, rapid breathing and vomiting. For complete
safety information, please see Credelio CAT product label or ask your
veterinarian.
Frequently Asked Questions
Credelio has a rapid onset of action and begins to kill fleas on dogs in just 4 hours. In cats, Credelio CAT begins killing fleas in just 6 hours. In a well‑controlled laboratory study, Credelio demonstrated 100% effectiveness against adult fleas within 12 hours (24 hours for cats) after administration or infestation and lasted for up to 35 days.
Credelio starts to kill ticks (Ixodes ricinus) within 4 hours of administration, with 98.7% of ticks killed within 8 hours.2
Not at all. Credelio and Credelio CAT kill adult fleas quickly and
effectively when used monthly according to label directions.
If there are fleas in your pet’s environment, it can take up to 6 weeks
for flea larvae to emerge and grow into adults. Credelio and Credelio CAT
kill adult fleas before they can lay eggs. If you see fleas on your pet,
they are most likely new adult fleas that will die very quickly.
All animals in the household should be treated with an approved flea product
to minimize the likelihood of flea re-infestation. It may also be necessary
to apply an approved flea treatment product to your carpet and furniture to
remove the presence of fleas in your dog’s or cat’s environment.
Maintain consistent monthly administration of Credelio or Credelio CAT to
provide continual flea protection in your pet.
For dogs, the small and tasty beef-flavored monthly chewable tablet was
accepted and tolerated by the 70 different dog breeds that were tested,
including Chihuahuas and Yorkshire Terriers.**
In a field trial, the acceptability of Credelio was tested at 10 different
locations across the U.S., and 94% of dogs accepted Credelio from the hand,
in the bowl or with food.3 The remaining 6% accepted Credelio when placed in
the mouth. There were no reports of unsuccessful dosing.
In cats, the chewable tablet was designed to be small and easy to give, with
a flavor and smell that cats find appealing.
In real-world testing, cat owners successfully administered 99.5% of tablets
to their cats. 46.9% of cats ate Credelio CAT on their own when offered by
hand, placed in an empty food bowl or with food. 52.6% of cats successfully
took the pill when placed in the mouth.
Yes, Credelio, Credelio CAT and Credelio Quattro are only available with a prescription from your veterinarian.
Unlike other chewable brands, Credelio Quattro contains four proven active ingredients (lotilaner, moxidectin, praziquantel, and pyrantel) to protect against 6 types of parasites.1
This monthly chewable tablet is available for puppies as young as 8 weeks old and weighing at least 3.3 lbs. Your vet will prescribe the right tablet size for your dog.
Give your dog the chewable tablet once a month with food or within 30 minutes of a meal. This ensures peak blood levels and sufficient exposure to lotilaner, which are critical for both initial and ongoing efficacy.
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